Magnesium salt combined together with stearic acid forms a compound referred to as magnesium stearate. This substance includes two parts of stearate and one part of magnesium in its structure.
At room temperature, magnesium stearate is a white colored powder. The compound is also called octadecanoic acid in natural chemistry.
Stearic acid is a type of saturated fatty acid, which exists naturally in foods such as cocoa butter, fish, meat, palm, egg, coconut etc.
Magnesium is an important mineral present in body; it is used for different body procedures. Food source of magnesium include spinach, nuts, fish, soybeans and so on.
What is Magnesium Stearate?
Magnesium stearate is a salt that is produced when a magnesium ion bonds with two stearate particles. Stearate is simply the anion type of stearic acid, which you’ve more than likely become aware of in the past.
Stearic acid is a long-chain saturated fat that is abundant in beef, cocoa butter, coconut oil, and other natural foods.
It’s likewise the only long-chain hydrogenated fat that scientists and doctors concur does not raise cholesterol levels, and does not increase risk of heart disease.
Magnesium stearate is most typically used in supplement manufacturing as a ‘circulation agent,’ which helps make sure that the equipment runs efficiently and the components remain mixed together in the proper percentages.
Magnesium strearate is extensively used in pharmaceutical market as a binding agent in making tablets, capsules, and powders.
It is due to the fact that of the lubricating properties, magnesium stearate has actually gotten wide acceptability in preparing pills and tablets.
It functions as an excipient; a non-active substance which binds the real medical ingredients in the pill or the tablet.
Besides its use in capsules and tablets in pharmaceutical market, magnesium stearate is likewise used for different other functions in minimal quantity. It is used as a stabilizer in preparing hard candies, talcum powder and formula, along with paints and varnishes.
There is a wide debate for its toxicity when it is used as a food and drug additive, though many people declare it to be a safe substance (Then I got to thinking, What is really the problem here?).
Magnesium Stearate Toxicity
Usually, magnesium stearate is safe; nevertheless, it is possible to formulate products and dietary supplements without its use. The only issue is it might take longer time along with changes in the preparatory technique of the solution.
Though there are no particular and validated hazardous impacts of magnesium stearate, which is used in tablets and pills, the likely unfortunate effects may be:
- It may worry from where magnesium stearate is isolated. The majority of the stearate is sourced from hydrogenation of saturated oils. While deriving it from the oils, there might be change of the compound and this modified substance may be hazardous to the body. Besides, the source from which it is obtained might have been treated with pesticides, for example cotton seed oil.
- There is no evidence that recommends the use of magnesium stearate is poisonous at the quantity which is discovered in the prescription medications and diet supplements. Some companies in a rush to prepare more capsules and tablets might add extra quantity of magnesium stearate for the better performance of the equipment. In such cases there may be negligible risk for overdose. For this reason always purchase products prepared by a reputed production company.
- Among the risks of magnesium stearate is that it might reduce the release capability of the drug. Nevertheless, the quantity of drug that needs to be absorbed in the blood is the same.
- Immunological problem: Ingestion in excess amount of magnesium stearate has actually been discovered to impact the T cells. T cells are responsible for maintaining healthy body resistance. This suggests high amount of magnesium stearate might act as immunosuppressant. However this study was done on cell culture with stearic acid. However this is not appropriate with oral consumption in people.
Allergy to Magnesium Stearate
Relating to the allergic problem of magnesium stearate, a hypersensitive individual may be allergic to any substance.
A 2012 study entitled “Magnesium stearate: an underestimated allergen” reported on a 28-year-old woman who had an allergy to magnesium stearate, resulting in hives.
Magnesium stearate may enter your body when you take pills and pills which are laced with it. If the body immune system acknowledges magnesium stearate as harmful it will cause an allergic reaction.
The allergic reaction might be in the kind of skin itching, running nose, shortness of breath and so on. Blood test and skin allergic reaction test are two methods through which you can conclude if it is caused due to magnesium stearate.
In case if a person dislikes it, then he has to avoid substances which has magnesium stearate. If you develop hives (or another allergic reaction) after consuming magnesium stearate, you ought to probably prevent it in the future.
Answer and Questions
Can you have an allergy to magnesium?
An extremely major allergic response to this drug is unusual. Nevertheless, seek instant medical attention if you observe any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing. This is not a complete list of possible negative effects.
Is stearic acid safe in dietary supplements?
Stearic acid has actually been found to have a positive result on the immune system, specifically on NK cell activity. In any case, despite whether the results on the immune system were positive or negative, the amount of stearic acid and magnesium stearate contained in dietary supplements is still too small to matter.
What are the side effects of magnesium?
According to the Office of Dietary Supplements, symptoms of magnesium overdose may consist of:
- Queasiness and vomiting.
- Muscle weak point.
- Irregular electrical conduction in the heart.
- Low high blood pressure.
- Urine retention.
- Respiratory distress.
Why is magnesium stearate bad for you?
Magnesium stearate is generally acknowledged as safe to consume. If you consume too much, it can have a laxative result. It can irritate the mucosal lining of your bowels. This causes your bowels to spasm, triggering a defecation or perhaps diarrhea.
Why is Magnesium helpful for you?
Magnesium is a nutrient that the body requires to remain healthy. Magnesium is essential for many procedures in the body, including controling muscle and nerve function, blood glucose levels, and high blood pressure and making protein, bone, and DNA.